Correlation of MRI image with the diagnosis of prostate cancer and tumor malignancy grade
10.3760/cma.j.issn.0254-9026.2016.08.012
- VernacularTitle:磁共振成像与前列腺癌诊断以及肿瘤恶性程度的相关性分析
- Author:
Ming LIU
;
Yaqing ZHANG
;
Huimin HOU
;
Chunmei LI
;
Min CHEN
;
Jianye WANG
- Publication Type:Journal Article
- Keywords:
Prostate neoplasms;
Magnetic resonance imaging;
Biopsy,needle
- From:
Chinese Journal of Geriatrics
2016;35(8):846-849
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation of MRI image with the detection rate of prostate cancer and cancer malignancy grade.Methods The prostate biopsy data of patients with prostate specific antigen (PSA) less than 20 μg/L were retrospectively analyzed.The correlations of MRI results with the cancer detection rate,Gleason score and tumor metastasis were analyzed and compared.Results Of 218 cases,88 prostate cancer patients (40.4%) were detected out by prostate puncture biopsy.In 126 MRI-positive prostate cancer patients,the detection rate of prostate cancer by prostate puncture biopsy was 57.9% (73 cases).In 92 MRI-negative prostate cancer patients,the detection rate of prostate cancer by prostate puncture biopsy was 16.3% (15 cases).The sensitivity,specificity,positive prognostic rate and negative prognostic rate by MRI were 82.95%,58.78%,57.94% and 83.70%,respectively.The area under receiver operating characteristic (ROC) curve for MRI to predict prostate cancer was 0.709.MRI results had a correlation with Gleason score.Conclusions MRI image has significant correlation with prostate cancer detection rate and Gleason score in patients with PSA less than 20 μg/L.