The clinical advancement of hypersplenism caused by posthepatitis cirrhosis
10.3760/cma.j.issn.1007-8118.2016.09.019
- VernacularTitle:肝炎后肝硬化所致脾功能亢进临床研究进展
- Author:
Xing LYU
;
Yong CHEN
- Publication Type:Journal Article
- Keywords:
Cirrhosis;
Hypersplenism;
Pathophysiology;
Treatment
- From:
Chinese Journal of Hepatobiliary Surgery
2016;22(9):642-645
- CountryChina
- Language:Chinese
-
Abstract:
Post-hepatitis cirrhosis (PHC),which results from either hepatitis B virus (HBV) or hepatitis C virus (HCV) infection,and its associated with hemodynamic changes may cause the spleen to become functionally hyperactive-a condition known as hypersplenism.Hypersplenism is associated with anemia,leukopenia,thrombocytopenia and splenomegaly.There are several effective methods to treat hypersplenism with the development of medical technology and the main purpose is the remission of hypersplenism,reducing the portal hypertension and decreasing the risk of hemorrhage.However,complete splenectomy or partial treatment of the hyperactive spleen is still controversial all over the world.This may be caused by the lack of the knowledge on the pathophysiological characteristics and clinical significance of treating hypersplenism.This review is a comprehensive discussion on the recent research which investigates hypersplenism caused by PHC.
