Clinical study of flurbiprofen axetl injection for the treatment of postoperative pain in patients with laparoscopic appendectomy
10.3760/cma.j.issn.1008-1372.2016.08.020
- VernacularTitle:氟比洛芬酯注射液用于治疗腹腔镜阑尾切除术术后疼痛的临床研究
- Author:
Caiping LIAO
- Publication Type:Journal Article
- Keywords:
Flurbiprofen/AD;
INJECTIO;
Laparoscopy/AE;
Appendectomy/AE;
Pain,postoperative/ET/DT
- From:
Journal of Chinese Physician
2016;18(8):1202-1204
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effects of flurbiprofen axetl injection on the treatment of postoperative pain in patients with laparoscopic appendectomy and on the platelet aggregation function.Methods From April 2013 to October 2015,100 laparoscopic appendectomy patients were randomly divided into observation and control groups,50 cases in each group.Observation group was injected flurbiprofen axetl injection 1 mg/kg,the control group was injected normal saline 5 ml.Analgesic effect,platelet aggregation function,and side effect were observed for two groups.Results Activities and resting visual analogue scale (VAS) score were significantly lower after flurbiprofen axetl injection in observation group (P ＜ 0.01),while activities and resting VAS score were not significantly decreased after normal saline used (P ＞ 0.05).Compared to those in control group,activities and resting VAS score at 30 min,1 h,2 h,4 h,and 6 h after flurbiprofen axetl injection in observation group were significantly lower (P ＜0.01).Platelet aggregation level before and after medication in two groups were no significant change (P ＞ 0.05).Drug side effects in two groups were no difference (P ＞ 0.05).Conclusions Patients with laparoscopic appendectomy do well with flurbiprofen axetl injection,and no obvious side effects.It is worthy of clinical application.
