Uterine natural killer cells and pregnancy
10.3760/cma.j.issn.1008-1372.2016.09.048
- VernacularTitle:人类子宫自然杀伤细胞与妊娠的研究进展
- Author:
Jing LIU
;
Tao MENG
- Publication Type:Journal Article
- Keywords:
Uterus;
Killer cells,natural;
Review
- From:
Journal of Chinese Physician
2016;18(9):1429-1431
- CountryChina
- Language:Chinese
-
Abstract:
Uterine natural killer cells (uNK) are distinct from peripheral blood NK (pbNK) cells,which constitute up to 70% of the decidual leukocyte population in the first half of pregnancy,and are considered to have a cytokine-secreting role rather than cytotoxic function.It plays an important role in trophoblast invasion and uterine spiral artery remodeling.As a result of imbalance of uNK cells,pathological pregnancy appeared.Herein,the origin of uNK cells and its function in pregnancy were veviewed.