Uterine natural killer cells and pregnancy
10.3760/cma.j.issn.1008-1372.2016.09.048
- VernacularTitle:人类子宫自然杀伤细胞与妊娠的研究进展
- Author:
Jing LIU
;
Tao MENG
- Publication Type:Journal Article
- Keywords:
Uterus;
Killer cells,natural;
Review
- From:
Journal of Chinese Physician
2016;18(9):1429-1431
- CountryChina
- Language:Chinese
-
Abstract:
Uterine natural killer cells (uNK) are distinct from peripheral blood NK (pbNK) cells,which constitute up to 70％ of the decidual leukocyte population in the first half of pregnancy,and are considered to have a cytokine-secreting role rather than cytotoxic function.It plays an important role in trophoblast invasion and uterine spiral artery remodeling.As a result of imbalance of uNK cells,pathological pregnancy appeared.Herein,the origin of uNK cells and its function in pregnancy were veviewed.
