Study progress of autoimmune hepatitis in children
10.3760/cma.j.issn.2095-428X.2016.20.022
- VernacularTitle:儿童自身免疫性肝炎研究进展
- Author:
Tingting ZOU
;
Xue ZHAN
- Publication Type:Journal Article
- Keywords:
Autoimmune hepatitis;
Clinical characteristics;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(20):1598-1600
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis (AIH) is a chronic and progressive inflammation of liver caused by the disorder of immunoregulation,and characterized by the presence of autoantibodies,elevated level of immunoglobulin G,and interface hepatitis histologically.As its clinical feature is not particular and the international diagnosis criteria is rarely applied in children,the diagnosis of pediatric AIH is difficult to make.It's essential for the good prognosis to recognize and diagnose the disease in early stage,as well as to treat it promptly and maintain regular follow-up.Now,the recent progress of pathogenesis,diagnostic criteria and management of AIH in children were summarized.