Medical treatment of peripheral precocious puberty
10.3760/cma.j.issn.2095-428X.2016.20.020
- VernacularTitle:外周性性早熟药物治疗
- Author:
Luhong YANG
;
Hui YAO
- Publication Type:Journal Article
- Keywords:
Peripheral precocious puberty;
Treatment;
McCune-Albright syndrome;
Familial male-limited precocious puberty
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(20):1591-1594
- CountryChina
- Language:Chinese
-
Abstract:
The etiology of peripheral precocious puberty(PPP) is complex and varied,which is mainly categorized into either genetic or acquired disorders.Albright-McCune syndrome and familial male-limited precocious puberty are the 2 most important genetic PPPs.The purposes of therapy are to halt pubertal development and restore sex steroids to prepubertal values and delayed rate of skeletal maturation in order to maximize height potential.The several major categories of clinical drugs for PPP include anti estrogen/androgen,estrogen receptor blocker,aromatase inhibitors and cytochrome P450 inhibitors and so on.
