Research progress of human leucocyte antigen genetic polymorphisms in children with Kawasaki disease
10.3760/cma.j.issn.2095-428X.2016.20.024
- VernacularTitle:川崎病患儿人类白细胞抗原基因多态性研究进展
- Author:
Shentang LI
;
Zuocheng YANG
- Publication Type:Journal Article
- Keywords:
Kawasaki disease;
Human leucocyte antigen;
Gene polymorphisms
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(19):1518-1520
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease (KD) is an acute febrile systemic vasculitis,and the cause of KD is not well understood.Based on epidemiologic studies and surveys,several features of KD strongly suggest a genetic component to disease pathogenesis.As a result of their involvement in immune response,human leucocyte antigen (HLA) genes have been extensively studied in association with outcomes of autoimmune and infectious diseases.HLA gene polymorphisms have also been reported to be associated with KD.Now,HLA gene polymorphisms related to KD is focused.
