Research progress in bone mesenchymal stem cell transplantation for the treatment of liver cirrhosis
10.3760/cma.j.issn.1673-4181.2016.04.010
- VernacularTitle:骨髓间充质干细胞移植治疗肝硬化的研究进展
- Author:
Xingwang ZHAO
;
Longlong ZHANG
;
Liang ZHANG
;
Tianyun LAN
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Bone mesenchymal stem cells;
Transplantation
- From:
International Journal of Biomedical Engineering
2016;39(4):239-243
- CountryChina
- Language:Chinese
-
Abstract:
Liver cirrhosis is a common chronic progressive liver disease,and at present the most effective treatment for advanced liver cirrhosis is liver transplantation.However,main reasons of limiting the wide application of liver cirrhosis are liver source deficiency,expensive cost,graft rejection reaction,the complications caused by long-term application of immunosuppressant and so on.Stem cell transplantation has become a new method for the treatment of liver diseases due to its beneficial to the damaged liver tissue repair,and it can compensate part of liver function.The basis and clinical research progress,the existing problems and prospects of the bone mesenchymal stem cell transplantation for the treatment of liver cirrhosis are summarized,aiming to provide theoretical basis for the further research.