Research progress of forming mechanism of agrC on Staphylococcus epidermidis biofilm
10.3760/cma.j.issn.1673-4181.2016.04.009
- VernacularTitle:agrC对表皮葡萄球菌生物膜形成作用机制的研究进展
- Author:
Peng CHEN
;
Lianhua YE
- Publication Type:Journal Article
- Keywords:
Staphylococcus epidermidis;
Bacterial biofilm;
Accessory gene regulator;
,Gene regulation mechanism
- From:
International Journal of Biomedical Engineering
2016;39(4):233-238
- CountryChina
- Language:Chinese
-
Abstract:
The formation of Staphylococcus epidermidis biofilm on the surface of medical biomaterials may resist the antibiotics treatment and cause chronic infection,which has become a research focus in recent years.Multiple genes constitute complex regulatory network which affect the biofilm formation,and play different roles in the different stages of biofilm formation.Accessory gene regulator (agr) is one of the most important genes in the process of biofilm formation.The process of bacterial biofilm formation,research status of regulation mechanism of agr system and its related genes in the formation of biofilm are reviewed,to provide reference of using agr as a target for the treatment of staphylococcus epidermidis biofilm related infections.
