Risk factors of electrocoagulation syndrome after endoscopic submucosal dissection in patients with colorectal lesions
10.3760/cma.j.issn.1671-7368.2016.09.010
- VernacularTitle:结直肠病变内镜黏膜下剥离术后电凝综合征的危险因素分析
- Author:
Mingzhu WANG
;
Shiyun TAN
;
Hesheng LUO
;
Ming LI
;
Pengbo WU
;
Fang GUO
;
Yongxiang SHU
- Publication Type:Journal Article
- Keywords:
Risk factors;
Endoscopic submucosal dissection;
Colorectal lesion;
Electrocoagulation syndrome
- From:
Chinese Journal of General Practitioners
2016;15(9):698-701
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of electrocoagulation syndrome after endoscopic submucosal dissection (ESD) in patients with colorectal lesions.Methods Clinical data of 145 patients with colorectal mucosal lesions undergoing ESD in People's Hospital of Wuhan University between September 2010 and September 2015 were retrospectively studied.Results Among 45 patients,post endoscopic submucosal dissection electrocoagulation syndrome (PEECS) was developed in 32 cases (22％).The median age in PEECS group was higher (t =-5.783,P =0.000),the median lesion size was larger(t =-5.590,P =0.000),the median length of hospital stay was longer (t =-6.841,P =0.000) than those in non-PEECS group.Univariate regression analysis showed PEECS was associated with the age,lesion size,lesion location,length of hospital stay,malignant tumor,polyps type,resection modality.Multivariable logistic regression analysis showed that the independent risk factors for the development of electrocoagulation syndrome were age ＞65 year (OR =1.123,95％ CI:1.013-1.244,P =0.027),lesion size ＞ 3.5 cm (OR =1.173,95％ CI:1.015-1.357,P =0.031),malignant tumor (OR =3.498,95 ％ CI:1.460-8.379,P =0.005),hospital stay ＞ 10 d (OR =2.480,95％ CI:1.346-4.569,P =0.004),non-rectal lesions (OR =12.612,95％ CI:3.446-46.157,P =0.000).Conclusion Attention should be paid for colorectal lesion patients with high risk of PEECS,when endoscopic submucosal dissection is performed.
