Risk factors analysis of restenosis after renal artery endovascular therapy in patients with Takayasu arteritis
10.3760/cma.j.issn.1007-631X.2016.10.006
- VernacularTitle:肾动脉型大动脉炎患者介入治疗后再狭窄的危险因素分析
- Author:
Yongpeng DIAO
;
Sheng YAN
;
Fuxian ZHANG
;
Yuexin CHEN
;
Zuoguan CHEN
;
Changwei LIU
;
Yongjun LI
- Publication Type:Journal Article
- Keywords:
Aortitis;
Angioplasty;
Risk factors;
Renal artery stenosis
- From:
Chinese Journal of General Surgery
2016;31(10):816-819
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of restenosis after renal artery endovascular treatment in patients with Takayasu arteritis.Methods In this study,39 patients with Takayasu arteritis underwent endovascular therapy from January 2003 to March 2014.Univariate and multivariate logistic regression analysis were used to analyze the risk factors relating to restenosis.Results There were 13 males and 26 females.The mean age was (27 ± 11) years.Seventeen unilateral and 22 bilateral renal artery stenosis were treated.A total of 54 endovascular procedures were successfully performed including 23 cases of unilateral percutaneous transluminal angioplasty (PTA),14 cases of unilateral stent implantation,12 cases of bilateral PTA,and 5 cases of bilateral stent implantation.The mean follow-up was (48 ±34) months,the restenosis rate was 38.9% (21.54) and the mean time of restenosis was (11.5 ± 2.3) months.Elevated erythrocyte sedimentation rate (ESR) (OR =6.624,95 % CI:1.222-35.902) was independent risk factors for restenosis.Antiplatelet therapy (OR =0.158,95% CI:0.028-0.887) and glucocorticoids or i mmunosuppressive therapy (OR =0.035,95 % CI:0.003-0.349) were protection factors against renal artery restenosis.Conclusion The elevated ESR increases the risk of restenosis after endovascular treatment in Takayasu arteritis associated renal artery stenosis.Antiplatelet therapy and glucocorticoids or immunosuppressive therapy were protection factors for renal artery restenosis.