Research of ribomomal protein L23 in tumor progression
10.3760/cma.j.issn.1673-422X.2016.11.008
- VernacularTitle:核糖体蛋白 L23参与肿瘤进程的研究
- Author:
Wenmiao PENG
;
Chuanrong QIN
;
Zhimin ZHANG
;
Meng HU
;
Zhiguo RAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Genes,p53;
Genes,myc;
Drug resistance,multiple;
Ribosomal protein L23
- From:
Journal of International Oncology
2016;43(11):835-837
- CountryChina
- Language:Chinese
-
Abstract:
Ribosomal protein L23 is a new target for gene therapy of cancer.It participates in tumor progression by activating p53,inactivating murine double minute 2,regulating the carcinogenic activity of c-Myc,inducing the multi-drug resistance,and affecting the biologic behaviour of tumors.Generally,it′s con-sidered to be a potential prognostic factor in human cancers.
