Aptamers as molecular probes in tumor molecular imaging
10.3760/cma.j.issn.1673-422X.2016.11.009
- VernacularTitle:基于适配子的分子探针在肿瘤分子影像学中的应用
- Author:
Yusheng SHI
;
Yonghua PENG
;
Shuyue SHENG
;
Xingmei ZHANG
- Publication Type:Journal Article
- Keywords:
Molecular probes;
Aptamers,nucleotide;
Neoplasms
- From:
Journal of International Oncology
2016;43(11):838-840
- CountryChina
- Language:Chinese
-
Abstract:
The ideal molecular imaging probe should have characteristics of specificity,sensitivity and safety.Aptamers are sing-strand DNA or RNA oligonucleotides which can bind their targets with high specificity and high affinity.Aptamers are new types of molecular imaging probe because they have many advantages,such as their large sum of possible targets,small molecule weights,easily production and modification,low immuno-genicity,high tissue penetration and so on.Now more and more aptamers research on tumor molecular imaging provides a new technology and tool for tumor diagnosis and therapy.
