Efficacy analysis of percutaneous microwave ablation in treatment of hepatic metastases from gastric adenocarcinoma after gastrectomy
10.3760/cma.j.jssn.1673-4904.2016.11.006
- VernacularTitle:微波消融治疗胃癌术后肝转移的临床疗效分析
- Author:
Meng ZHANG
;
Zhong GAO
;
Guifang TAN
;
Yong QIAN
;
Zhigang LIU
;
Yi ZHANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Neoplasm metastasis;
Microwave ablation
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(11):981-985
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of of percutaneous microwave ablation(MWA) in treatment of hepatic metastases from gastric adenocarcinoma after gastrectomy. Methods Twenty-four patients who underwent percutaneous MWA after gastrectomy for a hepatic metastasis from a gastric cancer from October 2009 to October 2014. Median age was (63 ± 11) years. Three-two times MWA was done in 27 metastatic tumors. Patients′ outcomes were assessed by enhancement CT or MRI. Results The rate of total ablation was 92.6%(25/27). The deadline of follow up was 2016-04-01. One patient was living and 23 patients died with tumor progression. The median overall survival was 24.1(95%CI:9.8-34.3) months. The survival rate of 1, 2, 3, 4 and 5 years was 78.7%, 40.7%, 38.5%, 19.4%and 8.2%. The median progression-free survival was 13.4 (95%CI:2.0-30.4) months, and the survival rate of local progression-free of 6 months, 1, 2 and 3 years was 64.3%, 50.1%, 40.2%and 26.9%. The main complication was moderate and severe pain in 10 cases, and 17 cases had post ablation syndrome. Conclusions For patients with metastatic tumors≤3 cm, MWA is a safe and feasible treatment option for hepatic metastases from gastric adenocarcinoma.
