The research development of vascular factors in recurrent spontaneous abortion

VernacularTitle:血管相关因素在复发性流产中的研究进展
Author: Shan WANG ; Caihong YU ; Xiaoxiao LI ; Meimei LIU
Publication Type:Journal Article
Keywords: Vascular endothelial growth factor receptor- 1; Abortion,habitual; Thrombospondin 1; Review
From: Chinese Journal of Postgraduates of Medicine 2016;39(11):1041-1043
CountryChina
Language:Chinese
Abstract: Recurrent spontaneous abortion (RSA) was one of the most difficult infertile diseases which was usually defined as consecutive still birth for more than three times during the first 20 weeks of gestation. Various factors and pathogeneses were thought to play a role in RSA. Recent studies had indicated that the disorders of blood vessel growth and the secondary abnormal blood perfusion may contribute to the occurrence of RSA. However, blood vessel growth was linked with the regulation of angiogenesis related factors. To provide references for the clinical prevention and treatment, the purpose of this paper was to evaluate the association between solubility vascular endothelial growth factor receptor-1(sflt-1), thrombospondin 1(TSP-1) and ovary, endometrial abnormal blood perfusion in cases of RSA.