Progress in Research on Guanylyl Cyclase C in Diagnosis and Treatment of Colorectal Cancer
10.3969/j.issn.1008-7125.2016.10.011
- VernacularTitle:鸟苷酸环化酶 C 在结直肠癌诊治中的研究进展
- Author:
Zhendong YAO
;
Min XU
- Publication Type:Journal Article
- Keywords:
Guanylate Cyclase C;
Colorectal Neoplasms;
Recurrence;
Neoplasm Metastasis;
Diagnosis;
Therapy
- From:
Chinese Journal of Gastroenterology
2016;21(10):626-628
- CountryChina
- Language:Chinese
-
Abstract:
Guanylyl cyclase C( GCC)is a specific intestinal tissue polypeptide expressed in intestinal epithelial cells,and is also expressed in colorectal cancer cell line and primary and metastatic colorectal cancer. Studies have indicated that level of GCC mRNA in blood could contribute to the early detection of colorectal cancer metastasis and recurrence,and is beneficial to the formulation of therapeutic regimen and follow-up. This article reviewed the progress in research on GCC in diagnosis and treatment of colorectal cancer.
