Efficacy evaluation criteria for immunotherapy in solid tumors
10.3760/cma.j.issn.1673-422X.2016.11.012
- VernacularTitle:实体瘤免疫治疗疗效评价标准
- Author:
Ping ZHANG
;
Bin AI
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Immunotherapy;
Response evaluation
- From:
Journal of International Oncology
2016;43(11):848-851
- CountryChina
- Language:Chinese
-
Abstract:
Immunotherapy has become an important therapy for solid tumors,which is in addition to surgery,radiotherapy,chemotherapy and targeted therapy.However immune treatment mechanism is different from those previous treatment.The effect of immunotherapies is on the immune system and not directly on the tumor.The kinetics of immunotherapy is characterized by a cellular immune response followed by potential changes in tumor burden and survival period.They are not captured by the traditional World Health Organiza-tion (WHO)or the Response Evaluation Criteria in Solid Tumors (RECIST).New immune-related response criteria are defined which more comprehensively capture all response patters and gradually applied in clinical practice.
