MicroRNAs and esophageal squamous cell carcinoma
10.3760/cma.j.issn.1673-422X.2016.11.015
- VernacularTitle:微小 RNA 与食管鳞状细胞癌
- Author:
Jun CHEN
;
Jie LI
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Esophageal neoplasms
- From:
Journal of International Oncology
2016;43(11):858-860
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs)can influence the proliferation,apoptosis,invasion and metastasis of esophageal squamous cell carcinoma (ESCC)cells by signal transduction,epithelial-mesenchymal transi-tion,angiogenesis and other regulating mechanisms.Specific serum miRNAs can serve as novel diagnostic and prognostic biomarkers of ESCC.Recent studies have indicated that miRNAs can improve the radiation sensitivi-ty and even reverse multi-drug resistance of ESCC,holding great clinical value.
