Effect of Deanxit in treatment of irritable bowel syndrome on hematological index and intestinal sensitivity
10.3969/j.issn.1005-1678.2016.09.011
- VernacularTitle:氟哌噻吨美利曲辛辅助治疗肠易激综合征对患者血液学指标及肠敏感度的影响
- Author:
Miaofang ZHANG
;
Miao ZHANG
- Publication Type:Journal Article
- Keywords:
Deanxit;
irritable bowel syndrome;
neuropeptide Y;
intestinal sensitivity
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(9):45-48
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Deanxit in treatment of Irritable bowel syndrome in patients in hematological index and intestinal sensitivity.Methods 82 cases with Irritable bowel syndrome were selected and divided into two groups, each had 41 cases.Control group was treated with conventional therapy, experiment group was treated on the base of the treatment with Deanxit.Hematology ndex and intestinal sensitivity index and clinical effect were compared after treatment.Results Compared with pre-treatment, plasma SS, SP and 5-HT decreased in two groups after treatment, NPY increased, levels of TNF-α, IL-6 and IL-8 decreased, levels of IL-10 increased, abdominal pain score, abdominal distension and diarrhea score score decreased, the differences were all significant(P<0.05).Compared with control group, plasma SS, SP and 5-HT in the experiment group were lower, NPY was higher, levels of TNF-α, IL-6 and IL-8 were lower, levels of IL-10 were higher, abdominal pain score, abdominal distension and diarrhea score score were lower than control group, the differences were all significant ( P <0.05 ) .Conclusion Deanxit in the treatment of Irritable bowel syndrome has curative effect.
