Clinical efficacy of short term intensive insulin pump therapy and biosynthetic human insulin therapy and its effect on maternal and neonatal outcomes in gestational diabetes mellitus

VernacularTitle:胰岛素泵短期强化干预联合生物合成人胰岛素治疗妊娠期糖尿病的临床疗效及对母婴结局的影响
Author: Qiuxia YANG ; Qian FANG
Publication Type:Journal Article
Keywords: insulin pump; short term intensive intervention; biosynthetic human insulin; gestational diabetes mellitus; maternal and neonatal outcomes
From: Chinese Journal of Biochemical Pharmaceutics 2016;36(9):135-137
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical effect of insulin on gestational diabetes mellitus(GDM).Methods GDM patients were randomly divided into group A and group B,group B were treated with short term intensive insulin pump therapy,and group A were treated with insulin pump in short term combined with biosynthetic human insulin therapy.Results The body mass index and diabetes family history rates pre-pregnancy in group B were significantly higher than group A(P<0.05).Logistic analysis showed that family history of BMI pre-pregnancy and diabetes family history were independent risk factors for GDM drug treatment(P<0.05).Compared with the group B,the improvement of blood glucose levels and the incidence of complications in patients with group A were better than the former(P<0.05).Conclusion Rational application of insulin can improve the efficacy of clinical treatment of GDM, reduce the incidence of complications, with high safety.