Clinical effect of glutamine supplemented parenteral alimentation support on postoperative recovery severe craniocerebral injury in ICU
10.3969/j.issn.1005-1678.2016.09.039
- VernacularTitle:添加谷氨酰胺的肠外营养支持在ICU重症颅脑损伤患者术后恢复中的临床效果
- Author:
Kang YIN
;
Qinglin XU
;
Hongquan ZHU
- Publication Type:Journal Article
- Keywords:
glutamine;
craniocerebral injury;
parenteral alimentation;
ICU
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(9):138-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of glutamine on parenteral alimentation in patients with severe craniocerebral injury in ICU. Methods 120 patients with severe brain injury in our hospital from November 2013 to November 2014 were selected as the research object.According to the random number table method, the 120 patients were divided into experimental group and control group, 60 cases in each group.The patients in the experimental group received glutamine parenteral nutrition support, while the control group received conventional parenteral nutritional support.The serum total protein, albumin, the complications and malnutrition-inflammation score(MIS) scores of the two groups were compared.Results The serum total protein and serum albumin levels of the experimental group post-treatment were significant higher than those in the control group (P<0.001).The complication rate in the experimental group was 15.0%, significantly lower than the control group of 55.0%(χ2 =21.099,P<0.001).The patients of normal MIS score in the experimental group were obviously superior to the control group ( 70.0% vs.33.3%, χ2 =16.151, P <0.001 ). Conclusion Adding glutamine to parenteral nutrition support therapy in the treatment of patients with severe craniocerebral injury can effectively improve the nutritional status after operation and strengthen nutrition support.
