Validation and Diagnostic Usefulness of Gastroesophageal Reflux Disease Questionnaire in a Primary Care Level in Mexico.
- Author:
Miguel Angel ZAVALA-GONZALES
1
;
Amyra Ali AZAMAR-JACOME
;
Arturo MEIXUEIRO-DAZA
;
Antonio Ramos DE LA MEDINA
;
Job REYES-HUERTA J
;
Federico ROESCH-DIETLEN
;
Jose Maria REMES-TROCHE
Author Information
- Publication Type:Original Article
- Keywords: Gastroesophageal reflux; Mexico; Questionnaires; Sensitivity and specificity
- MeSH: Comprehension; Diagnosis; Endoscopy; Esophagus; Gastroesophageal Reflux*; Heartburn; Humans; Mexico*; Primary Health Care*; Surveys and Questionnaires*; Sensitivity and Specificity
- From:Journal of Neurogastroenterology and Motility 2014;20(4):475-482
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Different non-invasive diagnostics strategies have been used to assess patients with gastroesophageal reflux. Gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a 6-item, easy to use questionnaire that was developed primarily as a diagnostic tool for GERD in primary care. Our aim was to validate and assess diagnostic utility of GerdQ questionnaire in Mexican patients in the primary care setting. METHODS: The study was performed in 3 phases: (1) a questionnaire translation and comprehension study (n = 20), (2) are a reproducibility and validation study (50 patients and 50 controls) and (3) a study to assess the clinical utility in 252 subjects with GERD symptoms. Diagnostic accuracy was calculated using endoscopy and/or pH-metry as the gold standard. RESULTS: Internal consistency measured by the Cronbach's alpha coefficient was 0.81 for patients and 0.90 for healthy controls, with a mixed coefficient of 0.93. Reproducibility for GerdQ was very good and its discriminating validity was 88%. Most of the patients with erosive reflux and non-erosive reflux with abnormal pH-metry had scores > 8, meanwhile most of the patients with functional heartburn and hypersensitive esophagus had < 8. Sensitivity, specificity and positive predictive value of GerdQ compared to the gold standard were 72%, 72% and 87%, respectively. CONCLUSIONS: In Mexico, the GerdQ questionnaire Spanish validated version is useful for GERD diagnosis in the primary care setting.
