Research progress in relationship between vitamin D and inflammatory bowel disease
10.3760/cma.j.issn.1674-635X.2016.04.012
- VernacularTitle:维生素D与炎症性肠病
- Author:
Shan TIAN
;
Weiguo DONG
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Inflammatory bowel diseases;
Immunoregulation;
Anti-inflammatory
- From:
Chinese Journal of Clinical Nutrition
2016;24(4):251-256
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD) is a group of chronic inflammatory diseases of the intestine mediated by abnormal immunological mechanism caused by multiple etiological factors.The main treatment at present is anti-inflammation and immunosuppression,but with severe side effects and poor efficacy.Vitamin D3 has immunoregulatory,anti-inflammatory,and antineoplastic functions.Vitamin D,as a novel immunoregulator,may provide a new treatment option for patients with IBD.This article will review the research progress on the following four aspects:the relationship of vitamin D with innate immunity,adaptive immunity,and pathogenesis of IBD,and vitamin D supplement in IBD patients.
