Analysis for Clinical Features and Prognosis of Taksyasu Arteritis Combining Neurological Symptoms
10.3969/j.issn.1000-3614.2016.10.012
- VernacularTitle:大动脉炎合并神经系统症状临床特点及预后分析
- Author:
Erpeng LIANG
;
Lirui YANG
;
Huimin ZHANG
;
Lei SONG
;
Haiyan QIAN
;
Yubao ZOU
;
Wenjun MA
;
Xiongjing JIANG
;
Haiying WU
;
Xianliang ZHOU
;
Jun CAI
;
Rutai HUI
;
Deyu ZHENG
- Publication Type:Journal Article
- Keywords:
Takayasu arteritis;
Neurological system;
Stroke
- From:
Chinese Circulation Journal
2016;31(10):997-1001
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the clinical features and prognosis in patients with Takayasu arteritis (TA) combining neurological symptoms. Methods: We retrospectively studied 274 TA patients combining neurological symptoms who admitted to our hospital from 2002-01 to 2013-10 for their clinical and imaging features with prognosis. Results: The ratio of male to female was 1:4.3 and the mean age of disease onset was at (28.2±11.2) years. The most common neurological symptom was dizziness (214/274 cases, 78.1%), most frequent type was type III TA (112 cases, 40.9%), most common affected artery was left subclavian artery (147 cases, 53.6%), and there were 77 cases (28.1%) with (3-4) branches of the aortic arch involvement. For stroke conditions, ischemic stroke was more frequently observed in patients with steno-occlusive lesions in subclavian artery and common carotid artery, while hemorrhagic stroke was more frequently found in patients with steno-occlusive lesions in descending aorta, abdominal aorta and/or renal artery. Heart failure was the most common cause of death, it was also the most common cardiovascular event in surviving cohorts. Conclusion: TA patients could have many neurological symptoms, which were related to the number and site of artery involvement.