Clinical Observation of Shuxuetong Injection in the Treatment of Acute Cerebral Infarction
10.6039/j.issn.1001-0408.2016.03.10
- VernacularTitle:疏血通注射液治疗急性脑梗死的临床观察
- Author:
Xi WANG
;
Chengji WU
;
Hongying LI
;
Jing WANG
;
Jun YANG
;
Hongxiu PAN
- Publication Type:Journal Article
- Keywords:
Shuxuetong injection;
Acute cerebral infarction;
Efficacy;
Safety
- From:
China Pharmacy
2016;27(3):316-318
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy and safety of Shuxuetong injection in the treatment of acute cerebral infarc-tion (ACI). METHODS:110 patients with ACI were randomly divided into control group and observation group. Control group was given mannitol,aspirin,atorvastatin,antidiabetic drugs and other conventional treatment;observation group was additionally given Shuxuetong injection 6 ml adding into 0.9% Sodium chloride solution 250 ml by intravenous infusion,3 times a day. The ef-ficacy in 2 groups was evaluated after 15 d,and the National Institute of Health Stroke Scale(NIHSS)score,neuron specific eno-lase(NSE),high-sensitivity C-reactive protein(hs-CRP)and tumor necrosis factor-α(TNF-α)levels before and after treatment and the incidence of adverse reactions in 2 groups were recorded. RESULTS:After treatment,NIHSS score,NSE,hs-CRP and TNF-αin 2 groups were significantly lower than before,and observation group was lower than control group,the differences were statisti-cally significant(P<0.05);total effective rate in observation group was significantly higher than control group,the difference was statistically significant(P<0.05). There was no obvious adverse reactions in 2 groups during treatment. CONCLUSIONS:Based on the conventional treatment,Shuxuetong injection has good efficacy and safety in the treatment of ACI.
