Study on the Quality Standard of Fufang Jinqin Tablet
10.6039/j.issn.1001-0408.2016.03.45
- VernacularTitle:复方金芩片的质量标准研究
- Author:
Xixi SI
;
Hongsheng SUN
- Publication Type:Journal Article
- Keywords:
Fufang jinqin tablet;
Baicalin;
TLC;
HPLC;
Quality standard
- From:
China Pharmacy
2016;27(3):415-417
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the quality standard of Fufang jinqin tablet. METHODS:TLC was conducted for the qual-itative identification of Cortex phellodendri and Lonicera japonica in the preparation. And HPLC was conducted for the content de-termination of baicalin;the column was Zorbax Eclipse XDB-C18 with mobile phase of methanol-0.2% phosphoric acid water(40:60,V/V)at a flow rate of 1.0 ml/min,the detection wavelength was 280 nm,column temperature was 35 ℃,and the injection vol-ume of 10 μl. RESULTS:C. phellodendri and L. japonica of TLC showed clear spots and good separation. The linear range of ba-icalin was 0.533-4.264 μg(r=0.999 9);RSDs of precision,stability and reproducibility tests were lower than 2%;recovery was 96.95%-99.70%(RSD=1.18%,n=6). CONCLUSIONS:The standard can be used for the quality control of Fufang jinqin tablet.
