Effects of Shenqi Fuzheng Injection Combined with Nimodipine on Blood Indicators of Cerebral Infarction Patients in the Recovery Period

VernacularTitle:参芪扶正注射液联合尼莫地平对脑梗死恢复期患者血液指标的影响
Author: Si CHEN ; Bin LU ; Wenwei YIN ; Kun BI
Publication Type:Journal Article
Keywords: Shenqi fuzheng injection; Nimodipine tablet; Cerebral infarction recovery period
From: China Pharmacy 2016;27(5):683-685
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To observe the effects of Shenqi fuzheng injection combined with Nimodipine tablet on blood indica-tors of cerebral infarction patients in the recovery period. METHODS:58 patients diagnosed as cerebral infarction in the recovery period were collected and randomly divided into control group and trial group,with 29 cases in each group. Control group was giv-en Nimodipine tablet 30 mg,tid;trial group was additionally given Shenqi fuzheng injection 250 ml,qd,ivgtt. Both group re-ceived 14 d of treatment. After treatment,the levels of serum hs-CRP,Fractalkine,tPA,PAI-1,blood rheology index and plasma fibrinogen(FIB)were observed in 2 groups. RESULTS:After treatment,the levels of serum hs-CRP,Fractalkine,blood rheology index PAI-1 and FIB decreased in trial group,while tPA activity increased;there was statistical significance between trial group and control group (P<0.05). CONCLUSIONS:Shenqi fuzheng injection combined with Nimodipine tablet can significantly im-prove the serum hs-CRP and Fractalkine levels,blood rheology indicators,PAI-1 and FIB,and improve tPA activity.