Effect of Prophylactic Use of Vitamin B6 with Chlorpheniramine on the Adverse Reactions in Fundus Fluores-cein Angiography
10.6039/j.issn.1001-0408.2015.36.09
- VernacularTitle:预防服用维生素B6联合氯苯那敏对荧光素眼底血管造影后不良反应的影响
- Author:
Junfeng ZHU
;
Xiaolu XIE
;
Xinyu LIU
;
Hongjie LIN
- Publication Type:Journal Article
- Keywords:
Fundus fluorescein angiography;
Prophylactic use;
Adverse reaction;
Vitamin B6;
Chlorpheniramine
- From:
China Pharmacy
2015;26(36):5069-5071
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the effect of prophylactic use of vitamin B6 with chlorpheniramine on the adverse reactions in fundus fluorescein angiography (FFA). METHODS:326 patients with FFA were randomly divided into observation group and control group. Observation group was orally given Vitamin B6 tablet 10 mg 30 min before angiography+Chlorpheniramine maleate tablet 4 mg;control group was orally given Metoclopramide tablet 10 mg+Chlorpheniramine maleate tablet 4 mg. The occurrence time and incidence of adverse reactions in 2 groups were observed and correlation analysis was conducted. RESULTS:There was no significant difference in the occurrence time of adverse reactions between 2 groups(P>0.05);the incidence of adverse reactions in observation group was significantly lower than control group,the difference was statistically significant(P<0.05). The correlation analysis of adverse reactions in control group showed the occurrence of adverse reactions had no correlation with age and gender of patients(P>0.05). CONCLUSIONS:Prophylactic use of vitamin B6 with chlorphenir arnine can reduce the occurrence of adverse reactions in FFA.
