Clinical Observation of Yinzhihuang Oral Liquid in the Adjuvant Treatment of Neonatal Breast-feeding Faun-dice
10.6039/j.issn.1001-0408.2015.36.17
- VernacularTitle:茵栀黄口服液辅助治疗新生儿母乳性黄疸的临床观察
- Author:
Weiwei TANG
;
Zongjie LYU
;
Zi WANG
;
Qian XIE
- Publication Type:Journal Article
- Keywords:
Yinzhihuang oral liquid;
Newborn;
Breast-feeding faundice;
Efficacy;
Safety
- From:
China Pharmacy
2015;26(36):5090-5092
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy and safety of Yinzhihuang oral liquid in the adjuvant treatment of neo-natal breast-feeding faundice. METHODS:112 newborns with faundice were randomly divided into control group and observation group. Control group stopped breast-feeding for 3 d and given artificial feeding,as well as keeping warm,nutritional support, maintaining water and electrolyte and acid-base balance,blue light irradiation and severe patients were given liver protection,en-zyme inducers;observation group was additionally given Yinzhihuang oral liquid 10 ml,twice a day. The treatment course was 7 d. Clinical efficacy,and serum total bilirubin(TBIL)level before and after treatment,and incidence of adverse reactions in 2 groups were observed. RESULTS:The total effective rate in observation group was significantly higher than control group,the difference was statistically significant(P<0.05). After treatment,TBIL level in 2 groups was significantly lower than before and gradually de-creased with time,and observation group was lower than control group,the differences were statistically significant(P<0.05). The incidence of adverse reactions of 2 groups was no statistically significant(P>0.05). CONCLUSIONS:Based on the conventional treatment,Yinzhihuang oral liquid can be used in the adjuvant treatment of neonatal breast-feeding faundice,with good efficacy and good safety.
