Clinical Observation of Jiedu Xiaoyu Cream Combined with Glucosamine Potassium Sulfate Capsules in the Treatment of Knee Osteoarthritis
10.6039/j.issn.1001-0408.2016.08.31
- VernacularTitle:解毒消瘀膏联合硫酸氨基葡萄糖钾胶囊治疗膝骨关节炎的临床观察
- Author:
Dehui XU
;
Dawei GU
;
Guochao YIN
;
Bo WANG
- Publication Type:Journal Article
- Keywords:
Knee osteoarthritis;
Jiedu xiaoyu cream;
Glucosamine potassium sulfate capsules;
Drug combination;
Efficacy
- From:
China Pharmacy
2016;27(8):1107-1109
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy and safety of Jiedu xiaoyu cream combined with Glucosamine potassium sulfate capsules in the treatment of knee osteoarthritis. METHODS:196 patients with knee osteoarthritis were randomly divided in-to observation group and control group,with 98 cases. Both group were given Glucosamine potassium sulfate capsules 0.5 mg/time, bid;observation group additionally received Jiedu xiaoyu cream for local use,once a week;control group additionally received Di-clofenac diethylamine emulsifiable paste for local use,bid. A treatment course lasted for 2 weeks,and both groups received 3 cours-es of treatment. Clinical efficacy,VAS scores,WOMAC scores and ADR of 2 groups were observed. RESULTS:The total effec-tive rate of observation group was 94.7%,which was significantly higher than that of control group(88.3%),with statistical sig-nificance(P<0.05). Compared with before treatment,VAS and WOMAC scores of 2 groups decreased obviously,with statistical significance(P<0.05);the decrease of observation group was more significant than that of control group,with statistical signifi-cance(P<0.05). There was no statistical significance in the incidence of ADR between 2 groups(P>0.05). CONCLUSIONS:Jie-du xiaoyu cream combined with Glucosamine potassium sulfate capsules has good clinical efficacy in the treatment of knee osteoar-thritis,can relieve knee pain and improve the function of activity.
