Efficacy Observation of Extracorporeal Shock Wave Lithotripsy Combined Use Paishi Decoction in the Treatment of Kidney Stone
10.6039/j.issn.1001-0408.2016.08.32
- VernacularTitle:体外震波碎石术后应用中药排石汤治疗肾结石患者的疗效观察
- Author:
Yawei LIU
;
Jiankun LI
;
Chunyan ZHAO
;
Chunxian WANG
- Publication Type:Journal Article
- Keywords:
Kidney stones;
Paishi decoction;
Extracorporeal shock wave lithotripsy;
Inflammatory factors;
T lymphocyte sub-sets;
Erythrocyte immune function
- From:
China Pharmacy
2016;27(8):1110-1112
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy of extracorporeal shock wave lithotripsy combined with Paishi decoction in the treatment of kidney stone. METHODS:160 patients with kidney stone were selected and randomly divided into observation group and control group,with 80 cases in each group. Control group only received HB-ESWL-VG extracorporeal shock wave litho-tripsy;observation group additionally received Paishi decoction 300 ml,tid,for consecutive 1 week,on the basis of control group. Clinical efficacy was observed in 2 groups;the levels of serum inflammatory factor IL-2,IL-6,TNF-α,T lymphocyte subset CD3+,CD4+,CD8+ and CD4+/CD8+,erythrocyte immune function indicator C3b receptor rosette(C3bRR),immunity complex ro-sette(ICR)and tumor erythrocyte rosette(TER)level were detected in 2 groups before and after treatment. RESULTS:The effec-tive rate of observation group(98.75%)was significantly higher than that of control group(91.25%),with statistical significance (P<0.05). After treatment,the levels of IL-2,IL-6 and TNF-α in observation group was significantly lower than in control group, the levels of CD3+,CD4+,CD4+/CD8+,C3bRR,ICR and TER were significantly higher than control group,with statistical signifi-cance(P<0.05). Comparsion of CD8+between 2 groups was not statistically significant(P>0.05). CONCLUSIONS:The extracor-poreal shock wave lithotripsy combined with Paishi decoction can relieve inflammation reaction,enhance immune function and im-prove therapeutic efficacy.
