Pharmaceutical Care Measures for Improving the Safety of Chemotherapy by Clinical Pharmacists
10.6039/j.issn.1001-0408.2016.08.39
- VernacularTitle:临床药师提高化疗用药安全的药学服务措施
- Author:
Qibing ZHANG
;
Jun YUAN
;
Lunbo LIU
;
Benmo YE
;
Shouning ZHAO
- Publication Type:Journal Article
- Keywords:
Clinical pharmacists;
Pharmaceutical care;
Chemotherapy;
Safety;
ADR
- From:
China Pharmacy
2016;27(8):1128-1130
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the measures and roles of pharmaceutical care in improving the safety of chemotherapy by clinical pharmacists. METHODS:Chemotherapy drug-induced ADR medical records were collected from oncology department of our hospital during Jan.-Dec. 2013 (before intervention) and Apr. 2014-Mar. 2015 (after intervention),and then analyzed and compared in respects of chemotherapy plan,patient’age and gender,route of administration,involved organs and systems,severe ADR,etc. RESULTS:After the formulation and implementation of pharmaceutical care for improving safe use of chemotherapy drugs,the incidence of chemotherapy drugs-induced ADR decreased from 88.48%to 72.14%;the incidence of ADR of involved di-gestive system,skin and its appendants decreased from 67.28% and 7.37% to 42.29% and 1.99%,respectively;the incidence of severe nausea and vomiting decreased from 27.65%to 18.91%;the constituent ratio of single agent chemotherapy and oral adminis-tration route increased from 31.80%(69/217) and 14.29%(31/217) to 44.28%(89/201) and 22.39%(45/201),respectively (P<0.05). CONCLUSIONS:Pharmaceutical care intervention measures formulated by clinical pharmacists can significantly lower the incidence of ADR,promote safe use of chemotherapy drugs and guarantee the safety of drug use.
