Intervention Effect of DRUGS System on Antibacterial Agents Use in Department of Obstetrics and Gyne-cology in Our Hospital
10.6039/j.issn.1001-0408.2016.08.41
- VernacularTitle:合理用药决策系统对我院妇产科抗菌药物使用的干预效果分析
- Author:
Fangqin XU
;
Chao GUO
;
Yang LU
;
Yanrong ZHU
;
Guo WEI
;
Miaomiao XI
;
Aidong WEN
- Publication Type:Journal Article
- Keywords:
Drug Rational Usage Guidelines System;
Antibacterial agents;
Department of obstetrics and gynecology;
Interven-tions
- From:
China Pharmacy
2016;27(8):1133-1135
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze intervention effect of Drug Rational Usage Guidelines System(DRUGS)on antibacterial agents use in department of obstetrics and gynecology in our hospital. METHODS:The application of antibacterial agents in depart-ment of obstetrics and gynecology in our hospital during Jan.-May(before intervention)and Jun.-Nov. 2012(after intervention)were extracted in respects of drug name,preoperative medication duration,perioperative additional condition,postoperative drug with-drawal time,drug combination,usage and dosage,average hospitalization stay,hospitalization cost. The intervention effects were analyzed. RESULTS:After intervention,the type of antibacterial agents were more in line with national regulations;the proportion of type Ⅰ incision surgery without antibacterial agents increased from 57.8% to 75.2%;the prophylactic application of antibacteri-al agents in type Ⅱ incision surgery within 0.5-2 h increased from 80.2% to 97.0%. The rate of reasonable antibacterial selection, drug combination,usage and dosage increased from 76.9%,64.9%,71.3% to 89.3%,84.6%,90.2%,respectively. The average hospitalization stay and antibacterial cost per capita decreased significantly. There was statistical significance among above indica-tors before and after intervention(P<0.05 or P<0.01). CONCLUSIONS:DRUGS effectively change irrational use of antibacterial agents in department of obstetrics and gynecology,which provide a new method for the management of antibacterial agents.