Clinical Observation Laparoscopy Combined with Dienogest and TCM in the Treatment of Endometriosis
10.6039/j.issn.1001-0408.2015.35.21
- VernacularTitle:腹腔镜联合地诺孕素和中药治疗子宫内膜异位症的临床观察
- Author:
Yuhong ZHANG
;
Xiaojuan LIU
;
Xibin SUN
;
Jiangping CHEN
;
Guiqing JIAO
- Publication Type:Journal Article
- Keywords:
Laparoscopy;
Dienogest;
TCM;
Endometriosis
- From:
China Pharmacy
2015;26(35):4960-4962
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare therapeutic efficacy and safety of laparoscopy combined with dienogest and laparoscopy combined with dienogest and TCM in the treatment of endometriosis. METHODS:126 endometriosis patients were selected and divid-ed into control group and observation group,with 63 cases in each group. Control group received combined with dienogest(25 mg/time,qd);observation group was additionally given TCM on the basis of control group. Therapeutic efficacy,recovery time of ovula-tion,menstrual recovery time and ADR were compared between 2 groups,and recurrence and pregnancy of them were followed up for 2 years. RESULTS:The total effective rate of observation group (93.65%) was significantly higher than that of control group (80.96%),with statistical significance (P<0.05). The menstrual recovery time and recovery time of ovulation in observation group were significantly shorter than control group,with statistical significance (P<0.05). The incidence of ADR in observation group (9.52%)was significantly lower than control group(26.98%),with statistical significance(P<0.05);the recurrence rate of observa-tion group (4.76%) was significantly lower than that of control group (17.46%),with statistical significance (P<0.05). In 2-year follow-up,there were 23 pregnancy patients in observation group,which was significantly higher than that of control group (9 cas-es),with statistical significance (P<0.05). CONCLUSIONS:Laparoscopy combined with dienogest and TCM in the treatment of endometriosis have better clinical effect,higher safety and lower recurrence rate. The patients are easily pregnant.
