Study on the Quality Standard of Shexiang Qutong Liniment
10.6039/j.issn.1001-0408.2016.12.35
- VernacularTitle:麝香祛痛搽剂的质量标准提高研究
- Author:
Nan ZHANG
;
Chengkang LEI
- Publication Type:Journal Article
- Keywords:
Shexiang qutong liniment;
Quality standard;
Improvement;
TLC;
GC
- From:
China Pharmacy
2016;27(12):1689-1691
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To improve the quality standard of Shexiang qutong liniment. METHODS:TLC was used for qualita-tive identification of Resina draconis and Rehmannia. The determination of total solids and ether-soluble extracts in the preparation was detected. GC was used for the content determination of muscone:the column was Thermo-TG-WAXMS capillary column by programmed temperature,the detector was FID detector,the detector temperature was 250 ℃,inlet temperature was 200 ℃,carri-er gas was high purity nitrogen at a flow rate of 1.0 ml/min,split ratio was 5:1,and the injection volume was 1 μl. RESULTS:The TLC pots of R.draconis and Rehmannia were clear with good separation. The total solids in preparations were not less than 0.6%,and extracts were not less than 3.0%. The linear range of muscone concentration was 15.21-243.36 μg/ml(r=0.9998);RS-Ds of precision,stability and reproducibility tests were lower than 2%;recovery was 97.70%-99.63%(RSD=0.78%,n=6). CON-CLUSIONS:The established method can be used for the quality control of Shexiang qutong liniment.
