Two Cases of Dermatomyositis Associated with Malignant Tumor.
- Author:
Min Chul KANG
1
;
Young Do PARK
;
Kyu Suk LEE
;
Sang Lip CHUNG
Author Information
1. Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. franzes@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Dermatomyositis;
Gallbladder cancer;
Small cell lung cancer
- MeSH:
Craniocerebral Trauma;
Dermatomyositis;
Follow-Up Studies;
Gallbladder Neoplasms;
Humans;
Liver;
Muscle Weakness;
Muscles;
Myositis;
Prognosis;
Skin;
Skin Manifestations;
Small Cell Lung Carcinoma
- From:Korean Journal of Dermatology
2008;46(8):1069-1074
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dematomyositis is an idiopathic inflammatory myopathy characterized by specific skin manifestations and progressive symmetric proximal muscle weakness. Importantly, dermatomyositis is occasionally associated with the internal malignant tumor, which is clearly correlated with poor prognosis. We report two cases of dermatomyositis, showing characteristic skin lesions, that associated with small cell lung cancer in a 64-year old man and gallbladder cancer in a 54-year old man, respectively. On laboratory findings muscle enzymes and liver function markers were elevated prominently. We tried to treat these patients with systemic corticosteroid and chemotherapy. The patient with small cell lung cancer died of SAH due to head trauma and in the case of the patient with gallbladder cancer, the symptoms of the muscle weakness and the skin lesions are getting better and worse repeatedly fluctuating and regular periodic follow up is required.
