Optimization of Spray Drying Process of Powder from the Raw Fruits Extracts of Psidium guajava by Re-sponse Surface Method
10.6039/j.issn.1001-0408.2015.34.29
- VernacularTitle:响应面法优化番石榴幼果提取液粉末原料喷雾干燥工艺Δ
- Author:
Dan SU
;
Guo XIE
;
Wenli LIU
;
Minzhi WU
- Publication Type:Journal Article
- Keywords:
Psidium guajava;
Raw fruits;
Extract;
Spray drying;
Process optimization;
Response surface method;
Total fla-vones;
Total polyphenol
- From:
China Pharmacy
2015;(34):4840-4843
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize spray drying process for the raw fruits extract of Psidium guajava. METHODS:Based on single factor,the response surface method was designed to optimize spray drying process condition,using extract rate as index and mass concentration,sampling temperature and sampling speed as factors. The contents and transport rate of total flavones and total polyphenol were determined in each step. RESULTS:The optimal process was as follows as mass concentration of 100 g/L, sampling temperature of 170 ℃,sampling speed of 180 ml/h. Under this condition,the yield of 3 batches of product was(56.08± 0.58)%(RSD=1.04%,n=3). The difference value between test value and predict value was 0.25,without significant difference (P>0.05). The powder of the raw fruits of P. guajava had high contents of total flavones [(17.80 ± 0.09)%] and total polyphenol [(1.23 ± 0.06)%]. The transport rates of them were 87.7% and 25.7%. CONCLUSIONS:Optimized process is feasible to obtain qualified product,and can be used to make medicinal solid preparation.
