Comparative Analysis of 552 Cases of Adverse Drug Reactions/Events Induced by Sodium Aescinate for Injec-tion and Instructions
10.6039/j.issn.1001-0408.2015.32.18
- VernacularTitle:552例注射用七叶皂苷钠致不良反应/事件及说明书对比分析
- Author:
Qiang LI
;
Li WANG
- Publication Type:Journal Article
- Keywords:
Sodium aescinate for injection;
ADR/ADEs;
Instruction;
Analysis
- From:
China Pharmacy
2015;(32):4515-4518
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for clinical safe administration and drug instruction revision through analyzing 552 cases of ADR/ADE induced by Sodium aescinate for injection. METHODS:Using“aescinate”and“ADR”as search words,re-trieved from CBM,CNKI,VIP and Wanfang database,47 literatures were included according to inclusion and exclusion criteria. The data was extracted and analyzed statistically. The drug instructions of twelve domestic pharmaceutical enterprises were analyzed statistically. RESULTS:The ADR/ADEs may involve multiple organs and systems,the most common reactions were venous irritant reactions as phlebitis,venous injury,etc. The drug instruction lacked some parts of information. CONCLUSIONS:Great impor-tance should be attaches to ADR/ADEs caused by Sodium aescinate for injection,and improvement of the drug instruction to en-sure the safety of drug use in the clinic.
