Analysis of 48 Cases of Lornoxicam-induced ADR in Beijing

VernacularTitle:北京地区氯诺昔康致不良反应48例分析
Author: Xifeng CUI ; Liqiu XING ; Chao MA ; Shurong ZHANG ; Chunyu LI
Publication Type:Journal Article
Keywords: Lornoxicam; ADR; Influencing factors; Safety analysis
From: China Pharmacy 2015;(32):4523-4525
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To investigate the characteristics and regularity of lornoxicam related ADR,and to provide reference for rational and safe use of lornoxicam. METHODS:From Jan. 1,2006 to Dec. 31,2013,lornoxicam related ADR reports collect-ed by National ADR Monitoring System in Beijing were analyzed retrospectively about their characteristics and related factors. RE-SULTS:In the statistical period,there were 48 ADR reports related to lornoxicam. The people over 40 years age accounted for 62.5%. 38 patients used lornoxicam by intravenous infusion or intramuscular injection ,accounting for 79.17%. The clinical mani-festations were diverse and complex,in which skin(32.96%)and gastrointestinal damage(25.00%)were more common ADR oc-curred within 30 min,accounting for 35.42%,and it would be better after stopping drug or 1-3 days symptomatic treatment. CON-CLUSIONS:The rational use of lornoxicam can reduce the occurrence of ADR. Suggestion on the use of the drug,is that the pa-tient should be monitored for security,in order to reduce the risk of ADR.