Comparison of Therapeutic Efficacy of Desflurane and Sevoflurane for Anesthesia of Elderly Patients
10.6039/j.issn.1001-0408.2015.32.27
- VernacularTitle:地氟烷与七氟烷用于老年患者麻醉的效果比较
- Author:
Xiulin YANG
;
Zhenyu XU
;
Bin YU
;
Yuqin ZHU
- Publication Type:Journal Article
- Keywords:
Desflurane;
Sevoflurane;
Anesthesia;
Elderly patients
- From:
China Pharmacy
2015;(32):4540-4542
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare therapeutic efficacy and safety of desflurane and sevoflurane for anesthesia of elderly pa-tients. METHODS:A randomized,parallel-controlled method was used,120 elderly patients undergoing anesthesia were random-ized into trial group and control group,with 60 cases in each group. Based on routine medication and disposal,control group was additionally given sevoflurane for anesthesia,and trial group given desflurane for anesthesia. The blood pressure and heart rate were recorded before anesthesia,2 min and 10 min after intubation,2 min and 30 min after the start of the operation;the extubation time,eye opening time,consciousness recovery time and postoperative complications were also recorded. RESULTS:10 min after intubation,the heart rate of trial group was significantly faster then that of control group,with statistical significance(P<0.05);the blood pressure and heart rate of 2 groups had no statistically significant difference between 2 groups at other time points(P>0.05). The extubation time and consciousness recovery time of trial group were significantly shorter than those of control group, with statistical significance(P<0.05). The postoperative complications mainly were hypopiesia,hypertension,bronchospasm,nau-sea and vomiting,and dysphoria;the incidence of postoperative complications in trial group and control group were 25.0% and 40.0%,with statistical significance (P<0.05). CONCLUSIONS:Desflurane is effective with less postoperative complications for the anesthesia of elderly patients.
