Effect Observation of Adjuvant Treatment of Xuebijing Injection for Severe Acute Pancreatitis
10.6039/j.issn.1001-0408.2015.32.30
- VernacularTitle:血必净注射液辅助治疗急性重症胰腺炎的疗效观察
- Author:
Hong CHEN
;
Suli WANG
;
Kunpeng ZHU
- Publication Type:Journal Article
- Keywords:
Xuebijing injection;
Severe acute pancreatitis;
Adjuvant treatment
- From:
China Pharmacy
2015;(32):4549-4550
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe therapeutic efficacy of adjuvant treatment of Xuebijing injection for severe acute pancreati-tis. METHODS:80 cases of severe acute pancreatitis were randomly divided into control group and observation group with 40 cas-es in each group. Control group was given symptomatic and supportive treatment,and observation group was additionally given in-travenous injection of Xuebijing injection 100 ml,twice a day,on the basis of control group. The levels of TNF-α,IL-6 and hs-CRP,organ failure were compared between 2 groups before and after treatment. RESULTS:There was no statistical significance in the levels of TNF-α,IL-6 and hs-CRP in 2 groups before treatment(P>0.05);after treatment,the levels of TNF-α,IL-6 and hs-CRP in observation group was significantly lower than control group and before treatment,with statistical significance (P<0.05). The proportion of renal function,respiration function and circulating failure in observation group were significantly lower than in control group,with statistical significance (P<0.05). CONCLUSIONS:Adjuvant treatment of Xuebijing injection for se-vere acute pancreatitis can significantly reduce the level of inflammation in the body and reduce organ damage.