Efficacy Observation of Xuebijing Injection in the Treatment of Severe Craniocerebral Trauma
10.6039/j.issn.1001-0408.2015.32.37
- VernacularTitle:血必净注射液治疗重症颅脑外伤患者的回顾性分析
- Author:
Jianguo CHEN
;
Wei SHI
;
Yu ZHANG
;
Jinlong SHI
;
Fei ZHOU
;
Lanchun NI
;
Jian CHEN
;
Qingfeng HUAN
- Publication Type:Journal Article
- Keywords:
Xuebijing;
Severe craniocerebral trauma;
Clinical value
- From:
China Pharmacy
2015;(32):4567-4569
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate therapeutic efficacy of Xuebijing injection in the treatment of severe craniocerebral trau-ma. METHODS:67 patients with severe craniocerebral trauma selected from neurosurgery department of our hospital were Treat-ment method divided into treatment group(33 cases)and control group(34 cases). Observation group was given conventional treat-ment,i.g. oxygen inhalation,dehydration,nourish cranial nerve,anti-infection. Treatment group On the basis of the control group was given Xuebijing injection 50 ml/time,tid,ivgtt. PT,TT,PLT,FIB,CK,LA, D-D,blood gas index (PaCO2,PaO2, HCO3-)of 2 groups were observed after 7 days of treatment,and prognosis of 2 groups were evaluated after 6 months as well as therapettin efficacy. RESULTS:After treatment,PT,TT,PLT,FIB,CK,LA, D-D,PaCO2,PaO2 and HCO3- of 2 groups were all better than before,and the treatment group was better than the control group,with statistical significance (P<0.05). The rate of good prognosis in treatment group (78.79%) was significantly better than in control group (55.88%) after 6 months of treat-ment,with statistical significance(P<0.05). CONCLUSIONS:Xuebijing injection in the treatment of severe craniocerebral trau-ma can improve coagulation function,blood gas levels and the inflammatory reaction,and is conducive to improve the patient's prognosis.
