Study on the Quality Standard of Jinwu Jiangu Capsule
10.6039/j.issn.1001-0408.2015.30.25
- VernacularTitle:金乌健骨胶囊的质量标准研究Δ
- Author:
Xunrong ZHOU
;
Liang YANG
- Publication Type:Journal Article
- Keywords:
Jinwu jiangu capsule;
Quality standard;
TLC;
HPLC;
Paeoniflorin;
Panax notoginseng;
Paeonia lactiflora;
Sino-menii Caulis
- From:
China Pharmacy
2015;(30):4247-4249
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the quality standard of Jinwu jiangu capsule. METHODS:Microscopy was used to identi-fy Panax notoginseng;TLC was used to identify Paeonia lactiflora and Sinomenii Caulis;HPLC was used to determine the content of paeoniflorin. The column was ZORBAX SB-C18 with mobile phase of acetonitrile-0.1% phosphoric acid(13∶87,V/V)at a flow rate of 1.0 ml/min,detection wavelength was 230 nm,column temperature was 30 ℃ and injection volume was 10 μl. RESULTS:Microscopy showed P. notoginseng had obvious features;P. lactiflora and Sinomenii Caulis in preparation were well-separated with clear spots. The linear range of paeoniflorin was 0.014-1.412 μg/μl(r=0.999 2);RSDs of precision,stability and reproducibility tests were lower than 2%;recovery was 95.73%-99.48%(RSD=1.54%,n=6). CONCLUSIONS:The method is simple,accurate and reproducible,and can be used for the quality control of Jinwu jiangu capsule.
