Content Determination of Menthol in 56 Batches of Qiangli Pipa Syrup by HS-GC
10.6039/j.issn.1001-0408.2015.30.40
- VernacularTitle:顶空气相色谱法测定市售56批次强力枇杷露中薄荷脑的含量
- Author:
Xinli CHAI
;
Chunxian ZHU
;
Lingli JIANG
;
Jianfeng SONG
- Publication Type:Journal Article
- Keywords:
Qiangli Pipa syrup;
HS-GC;
Menthol;
Content determination
- From:
China Pharmacy
2015;(30):4288-4290
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the HS-GC method for the content determination of menthol in Qiangli Pipa syrup,and the content of menthol in 56 batches of Qiangli Pipa syrup commercially available was determined. METHODS:HS-GC was per-formed on the column of Agilent HP-INNOWAX,column temperature was 130 ℃(maintaining 7 min),FID was used as detector, inlet temperature was 200 ℃,detector temperature was 250 ℃,carrier gas was high-purity nitrogen,flow rate was 3 ml/min,split ratio was 10∶1 and the injection volume was 1 000 μl. RESULTS:The linear range of menthol was 0.007 07-0.141 40 mg/ml(r=0.999 1);RSDs of precision,reproducibility and stability tests were no more than 3.37%;average recovery was 94.3%-99.6%(RSD=1.86%,n=6). There was significant difference in the contents of menthol in 56 batches Qiangli Pipa syrup. CONCLU-SIONS:The method is simple,sensitive,accurate and reliable,and can be used for content determination of menthol in Qiangli Pi-pa syrup. The sampling results show it is necessary to update the detecting items for the content of Qiangli pipa loquat and strength-en the quality control of it.
