Optimization of the Extraction Technology of Astilbin in Puling Penyankang Capsules by Orthogonal Test
10.6039/j.issn.1001-0408.2015.31.33
- VernacularTitle:正交试验优选蒲苓盆炎康胶囊中落新妇苷的提取工艺
- Author:
Guangming HAN
;
Yanyan ZHANG
;
Jiaxiu LIU
- Publication Type:Journal Article
- Keywords:
Puling penyankang capsules;
Smilacis glabrae rhizoma;
Astilbin;
Extraction amount;
Extraction technology;
Yield of extractum;
Orthogonal test
- From:
China Pharmacy
2015;26(31):4421-4423
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the extraction technology of astilbin from medicinal herbs in Puling penyankang cap-sules. METHODS:The extraction technology of astilbin from ingredients(Smilacis glabrae rhizoma,chuanxiong rhizoma,Eucom-miae cortex,notoginseng radix et rhizoma,Plantaginis semen)of Puling penyankang capsules was optimized with concentration of ethanol,immersion time and percolation speed as factors,and using the yield of extractum and the extraction amount of astilbin as index. RESULTS:The optimized extraction technology was as follows as 2-fold 70% ethanol,immersed for 24 h,percolated with 70% ethanol with percolation speed of 3 ml/min,10-fold percolate volume was colleted. In verification test,the yield of extractum were 6.79%,6.92% and 6.84%,respectively,with average value of (6.85 ± 0.96)%(n=3);the extraction amounts of astilbin were 39.23,39.67 and 39.69 mg,with average value of (39.53 ± 0.66) mg (n=3). CONCLUSIONS:The optimized extraction technology of astilbin in Puling penyankang capsules is stable and practical.
