Optimization of Water Extraction Technology of Medicinal Material in Lian-wei Anacyclus Formulation
10.6039/j.issn.1001-0408.2015.25.32
- VernacularTitle:莲威阿那其处方药材水提工艺优化
- Author:
Xiaoyue JIN
;
Huayang WANG
;
Dongsheng GENG
- Publication Type:Journal Article
- Keywords:
Lian-wei anacyclus;
Orthogonal experiment;
Water extraction technology;
Optimization
- From:
China Pharmacy
2015;(25):3551-3553
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the water extraction process of medicine in lian-wei anacyclus prescription. METHODS:Composite score of polysaccharide content and raw polysaccharide were set as investigation index,the different adding water amount,extracting times and extraction duration were set as investigation factors,and L9(34)orthogonal test were conducted to op-timize the water extraction technology of medicine in lian-wei anacyclus prescription and verification test was carried out. RE-SULTS:Extracting times had the most significant effect on the investigation index;the most optimized process was as follows as 12 times of adding water amount,2.0 h of extracting times,3 times of extraction. The average content of polysaccharide was 36.34μg/ml(RSD=0.24%,n=3)in the verification test,and the average content of raw polysaccharide was 10.18%(RSD=0.65%, n=3). CONCLUSIONS:The optimized technology is reasonable,feasible and reproducible,and can provide reference for the dos-age form transformation.
