Analysis of 35 Reports of Adverse Drug Reactions Induced by Shuxuetong Injection

VernacularTitle:疏血通注射液致不良反应35例报告分析
Author: Jing ZHANG ; Na MEI ; Jinghong WANG ; Xiao ZHANG
Publication Type:Journal Article
Keywords: Shuxuetong injection; Adverse drug reactions; Analysis
From: China Pharmacy 2015;(24):3363-3365
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To analyze the rules and characteristics of adverse drug reactions(ADR)induced by Shuxuetong in-jection,and provide reference for clinical rational drug use. METHODS:ADR cases induced by Shuxuetong injection in Beijing collected by national ADR monitoring center in 2012 were retrieved,and 35 cases of the ADR were statistically analyzed. RE-SULTS:ADR induced by Shuxuetong injection had relatively high incidence in elder over 60 years old(68.57%);ADR might oc-curred after 5 min with off-label use and it mainly occured after 10 min-2 h(40.00%);clinical manifestations were mainly systemic damage and nervous system damage,and all patients were returned to normal after symptomatic treatment except one with unclear outcome. CONCLUSIONS:ADR induced by Shuxuetong injection is related to age and dosage. Clinical medication should be strict-ly in accordance with the instructions,strengthen medication monitoring and reduce incidence of ADR to ensure medication safety.