Analysis of the Cost-effectiveness of 2 Kinds Regimens in the Treatment of Brain Trauma and Cerebral Hem-orrhage Complicated with Upper Gastrointestinal Hemorrhage
10.6039/j.issn.1001-0408.2015.24.21
- VernacularTitle:2种方案治疗脑外伤和脑出血并发上消化道出血的成本-效果分析
- Author:
Linzhong YU
;
Hong ZHANG
;
Liping WU
;
Jindong SONG
;
Weiliang SHEN
;
Chunfeng JI
- Publication Type:Journal Article
- Keywords:
Omeprazole;
Esomeprazole;
Brain trauma cerebral hemorrhage complicated with upper gastrointestinal hemorrhage;
Analysis of cost-effectiveness
- From:
China Pharmacy
2015;(24):3366-3367
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy and economy of omeprazole and esomeprazole in the treatment of brain trauma and cerebral hemorrhage complicated with upper gastrointestinal hemorrhage. METHODS:The data of 110 patients with trauma cere-bral hemorrhage complicated with upper gastrointestinal hemorrhage were retrospectively analyzed and divided into omeprazole group (56 cases)and esomeprazole group(54 cases). All patients were given conventional treatment. On this basis,omeprazole group was treated with Omeprazole for injection 40 mg by intravenous infusion;esomeprazole group was treated with Esomeprazole injection 40 mg by intravenous infusion,twice a day. The treatment course for 2 groups was 5 d. The efficacy and economy of patients were com-pared. RESULTS:The total effective rates in esomeprazole group were significantly higher than omeprazole group higher,the cost-ef-fectiveness in esomeprazde group(1 397.71)were significantly lower than omeprazole group(1 512.09)(P<0.05),andΔC/ΔE=91.52. CONCLUSIONS:Esomeprazole has good efficacy,safety and economy in the treatment of brain trauma cerebral hemorrhage compli-cated with upper gastrointestinal hemorrhage.
