Triamcinolone-Induced Intraocular Pressure Elevation: Intravitreal Injection for Macular Edema and Posterior Subtenon Injection for Uveitis.
- Author:
Seung Youn JEA
1
;
Ik Soo BYON
;
Boo Sup OUM
Author Information
- Publication Type:Original Article ; Comparative Study
- Keywords: Intraocular pressure; Intravitreal injection; Subtenon injection; Triamcinolon acetonide
- MeSH: Vitreous Body; Uveitis, Posterior/*drug therapy/pathology; Triamcinolone Acetonide/administration & dosage/*adverse effects; Time Factors; Retrospective Studies; Orbit; Ocular Hypertension/*chemically induced/physiopathology; Middle Aged; Male; Macular Edema, Cystoid/*drug therapy/pathology; Intraocular Pressure/*drug effects; Injections; Humans; Glucocorticoids/administration & dosage/*adverse effects; Follow-Up Studies; Female; Aged, 80 and over; Aged; Adult
- From:Korean Journal of Ophthalmology 2006;20(2):99-103
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: To assess the effect of intravitreal and posterior subtenon injections of triamcinolone acetonide (TA) on intraocular pressure (IOP). METHODS: we reviewed 42 consecutive eyes after intravitreal TA injection (IVTA) and 43 eyes following posterior subtenon TA injection (PSTA). All cases had a minimum follow-up time of three months. After injection, the value and time of the maximal IOP, the amount of IOP elevation and the needs of the medication were assessed. RESULTS: The IOP increased significantly (p<0.001) from 16.3+/-2.5 mmHg preoperatively to a mean maximum of 21.7+/-5.3 mmHg in the IVTA group, and from 15.3+/-4.5 mmHg to 20.6+/-3.0 mmHg in the PSTA group. An elevation in the IOP of more than 5 mmHg from the baseline IOP was seen in 52.4% of the IVTA group at a mean time of 3.1 weeks postoperatively, and 44.2% of the PSTA group displayed an IOP elevation at 5.9 weeks. CONCLUSIONS: Both developed significant elevations of IOP, but this appeared at a later date in the PSTA group. Careful follow-up after local injection of steroids is necessary.
