Analysis of Drug-resistant Bacteria Monitoring and Early Warning and Clinical Application of Antibacterial Drugs in Our Hospital in 2014
10.6039/j.issn.1001-0408.2015.23.15
- VernacularTitle:我院2014年耐药菌监测预警及抗菌药物临床应用分析
- Author:
Xuemei HUANG
- Publication Type:Journal Article
- Keywords:
Drug-resistant bacteria;
Analysis;
Antibacterial drug;
Reasonable application
- From:
China Pharmacy
2015;(23):3213-3215
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for clinical rational drug use. METHODS:Combined with bacterial drug resis-tance monitoring data in our hospital in 2014,the varieties,the amount of antibacterial drug,DDDs and other index were analyzed retrospectively for the same period. RESULTS:The detection rate of Gram-negative bacteria (79.27%) was higher than that of Gram-positive bacteria (20.73%);the most common Gram-negative bacilli and Gram-positive cocci were Escherichia coli (38.62%) and Staphylococcus aureus (5.22%). Pseudomonas aeruginosa and Stenotrophomonas maltophilia were the most com-mon non-fermentation bacteria;Main Gram positive bacteria were most sensitive to vancomycin,tigecycline and furadantin,etc. Main Gram-negative bacteria were most sensitive to imipenem,ertapenem,etc. Top 3 antibacterial drug in the list of DDDs were Levofloxacin injection,Cefazolin injection,Cefoperazone/sodium sulbactam for injection. CONCLUSIONS:Third generation of cephalosporins are used frequently in our hospital,which is a major cause of ESBLs producing and drug resistance,bacterial drug resistance monitoring and early warning data has played a positive role on guiding reasonable application of antibacterial drug in our hospital.
